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Drug Rehab May Soon Include Pharmacogenetics

Drug Rehab May Soon Include Pharmacogenetics

Pharmacogenetics looks at genetic variation to predict individual differences in response to medications. Individuals may metabolize the same medication in different ways, and their genotype may indicate some of these differences in drug metabolism. Proponents of pharmacogenetics hope that this relatively new field of study will lead to increased efficacy and safety for a wide […]

Will an Anti-cocaine Vaccine Improve Drug Treatment?

Will an Anti-cocaine Vaccine Improve Drug Treatment?

A clinical trial supported by the National Institute on Drug Abuse (NIDA) marks the first successful, placebo-controlled demonstration of a vaccine against illicit drug addiction. The anti-cocaine vaccine causes the immune system to produces antibodies that attach to cocaine molecules, preventing them from entering the brain. Thus, the vaccine blocks the drug’s effect.   The […]

Predictors of response to naltrexone in alcohol rehab

Predictors of response to naltrexone in alcohol rehab

Naltrexone is commonly prescribed in alcohol rehab. It is an opioid receptor antagonist that blocks opioid receptors and thus blocks the feeling of pleasure derived from alcohol consumption. Several double-blind clinical trials have shown that naltrexone is more effective than placebo in treatment for alcohol dependence. However, naltrexone may not work well for everyone. Its […]

High-dose baclofen for alcohol treatment

High-dose baclofen for alcohol treatment

Oliver Ameisen, an associate professor of medicine and cardiologist at Weill Medical College of Cornell University, reported in Alcohol and Alcoholism that he successfully used high-dose baclofen for alcohol treatment and achieved complete and prolonged suppression of symptoms of his own alcohol dependence (2005). You may also be interested in: Ameisen had been diagnosed with […]

Kudzu vine extract for alcohol treatment

Kudzu vine extract for alcohol treatment

Daidzin, a compound found in the kudzu vine, interferes with the metabolization of alcohol and produces effects similar to those of the anti-drinking drug Antabuse. Dr. Ting-Kai Li of Duke University and Dr. Ivan Diamond of the University of California in San Francisco believe that they have discovered a synthetic version of daidzin that reduces […]

Naltrexone and acamprosate combination in alcohol treatment

Naltrexone and acamprosate combination in alcohol treatment

The use of Naltrexone and/or acamprosate can be helpful during alcohol treatment, however, to achieve the greatest success, individuals would benefit from incorporating psychological intervention. Evidence-based addiction treatment incorporates cognitive behavior therapy (CBT) which enables individuals to learn ways to cope with cravings and eventually have greater success for alcohol recovery. You might also be […]

A one-year trial of naltrexone vs disulfiram in alcohol treatment

A one-year trial of naltrexone vs disulfiram in alcohol treatment

Using evidence-based addiction treatment, individuals can learn a self-empowering approach to overcome addiction. Naltrexone vs Disulfiram Naltrexone and disulfiram are both used as deterrent agents in addiction treatment. Naltrexone is an opioid receptor agonist that reduces the euphoria associated with alcohol consumption and thus reduces the risk of relapse in alcohol-dependent individuals. Disulfiram blocks the […]